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Natural Products Research

Natural fernNatural products are researched for many reasons, from biodiversity preservation through flavour or fragrance research, to finding a cure for disease.  Whatever your reason, Genevac systems are used by researchers who are investigating the properties of the natural environment.
 

For basic botanical and biological research, the miVac concentrator range are the mainstay for those extracting and purifying DNA or proteins for genome and proteome research.

 
Genevac systems are widely used by researchers seeking to extract functional molecules from natural sources.  A typical process would be to take a tissue (or micro-organism broth) sample and then perform a primary solvent extraction resulting in a large volume of crude extract.  The crude extract is often concentrated, for which the Rocket Evaporator is ideal, before being fractionated to isolate each component.  Fractionation may use a system such at the Sepbox, one, or two dimensional chromatography which produces many samples from one extract.  These samples need to be evaporated before storage or analysis and may require lyophilisation. Genevac HT series evaporators are used for this purpose.
 
Useful Papers:

Useful Links:

  • High-Throughput Method for the Production and Analysis of Large Natural Product Libraries for Drug Discovery.  Eldridge et al. published in Anal. Chem., 2002, 74 (16), pp 3963–3971.
  • The EZ-2 at work in the Kerr Laboratory for Marine Natural Product research at University of Prince Edward Island, Canada

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